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Tag: clinical trial

No. 25 – Estimands Part 2 – What Exactly Is an Estimand?

The word estimand has exploded into the vernacular of statistical thinking for clinical trials in the last decade or so. Where did it come from and why is it so important now?

Steve Ruberg Estimands, Uncategorized 2 Comments July 2, 2026July 12, 2026 9 Minutes

No. 19: We Won’t Get Fooled Again, Again

Many clinician researchers are attempting to "repurpose" old treatments for COVID-19. How shold we evaluate purported positive findings in a small, but rigorous, clinical trial?

Steve Ruberg Are You Sure?, Bayesian Thinking, Case Studies Leave a comment March 9, 2021July 2, 2026 13 Minutes

No. 6: Détente – The Peaceful Co-Existence of Significance Levels and Bayes

pr(B|A) ≠ 1 – pr(A|B). Why do we act like it ?!

Steve Ruberg Bayesian Thinking Leave a comment July 31, 2019August 16, 2019 7 Minutes
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